Final adult height in long-term growth hormone-treated achondroplasia patients
نویسندگان
چکیده
منابع مشابه
Final height in children with medulloblastoma treated with growth hormone.
BACKGROUND Medulloblastoma is the most frequent primary solid central nervous system tumour in children. The 5-year survival rate is at present at about 60%. Height in general is severely compromised in survivors. The present study is an extension of the investigation by the author's group of the effect of exogenous growth hormone (GH) among medulloblastoma patients. METHODS A total of 113 pa...
متن کاملFinal adult height in children with congenital adrenal hyperplasia treated with growth hormone.
CONTEXT Patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency typically reach a final adult height well below their mid-parental target height. OBJECTIVE The objective of this study was to examine whether GH alone or in combination with an LHRH analog (LHRHa) improved the final adult height in patients with CAH. DESIGN The study was a nonrandomized prospective ...
متن کاملFinal height in growth-hormone-treated children with idiopathic growth hormone deficiency: the Malaysian experience.
479 INTRODUCTION Growth hormone has been used in the treatment of short stature since 1957 . Prior to 1985, human cadaver-derived pituitary growth hormone was used. Recombinant human growth hormone which was approved in 1985 made available a reliable, virtually unlimited resource to replace human pituitary growth hormone (which was withdrawn due to reported cases of Creutzfeldt-Jakob disease). ...
متن کاملLong-term follow-up results of growth hormone therapy for patients with adult growth hormone deficiency.
OBJECTIVE We evaluated the long-term effects of growth hormone (GH) on markers of quality of life, glucose metabolism, and lipid metabolism to validate the adequacy of long-term GH replacement therapy for adult GH deficiency (AGHD). DESIGN Eighty-three of 100 sequentially followed patients who received GH therapy were selected for this study. Forty-nine were men aged 26 to 78 years (mean, 52 ...
متن کاملFinal height in girls with turner syndrome after long-term growth hormone treatment in three dosages and low dose estrogens.
Although GH treatment for short stature in Turner syndrome is an accepted treatment in many countries, which GH dosage to use and which age to start puberty induction are issues of debate. This study shows final height (FH) in 60 girls with Turner syndrome treated in a randomized dose-response trial, combining GH treatment with low dose estrogens at a relatively young age. Girls were randomly a...
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ژورنال
عنوان ژورنال: European Journal of Pediatrics
سال: 2017
ISSN: 0340-6199,1432-1076
DOI: 10.1007/s00431-017-2923-y